Acknowledgement

Supported by an educational grant from Alnylam Pharmaceuticals, BridgeBio Pharma, Inc, and held in partnership with the Association of Black Cardiologists, Inc. (ABC)

Target Audience

The educational design of this activity addresses the needs of U.S. based healthcare professionals, including internists, family practice physicians, cardiologists, lipidologists, and advanced practice providers.

Learning Objectives

Define the pathophysiology, prevalence, and types of transthyretin cardiac amyloidosis (ATTR-CM)
Recognize the disproportionate burden of ATTR-CM in African Americans and the significance of Val122l mutation
List screening and diagnostic methods to optimize the early identification of patients with ATTR-CM, including the African American population, based on guidelines
Review the different options for the treatment of ATTR-CM, including new and emerging novel targeted agents
Select the best treatment for ATTR-CM patients, particularly African Americans, to optimize clinical outcomes

Financial Disclosures

Partners requires every individual in a position to control educational content to disclose all financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

All relevant financial relationships for anyone with the ability to control the content of this educational activity are listed below and have been mitigated according to Partners policies. Others involved in the planning of this activity have no relevant financial relationships.

Faculty Disclosure

Dr. Ferdinand, faculty for this educational activity, discloses the following:

Consultant, Advisor, Speaker: Amgen, Novartis, Boehringer Ingelheim, Medtronic, AstraZeneca

Dr. Akinboboye, faculty for this educational activity, discloses the following:

Consultant, Advisor, Speaker: Alnylam Pharmaceuticals, Astra Zeneca, Bridgebio, Pfizer Inc.

Dr. Ruberg, faculty for this educational activity, discloses the following:

Researcher: BridgeBio Pharm, TriNetX/AstraZeneca, Anumana, Pfizer
Consultant, Advisor, Speaker: eMyosound, Attralus

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications. The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Additional Disclosures

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

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Innovative Approaches to ATTR-CM: Addressing Health Disparities in African American Populations

Video